IHU

Presentation of the IHU Bordeaux

Liryc is a research, treatment, innovation and teaching institute, wholly dedicated to the study, diagnosis and treatment of cardiac electrical disorders, headed by Professor Michel Haissaguerre. These electrical disorders are responsible for various cardiovascular diseases and sudden deaths and cause, directly or indirectly, around one third of all deaths in the world.

 

At the international level, there are currently not enough research centers studying cardiac electrical activity. 90% of cardiac research centers focus on muscular contraction or mechanical or vascular functions. We are convinced that the study of this delicate electrical balance is fundamental in advancing cardiovascular pathology knowledge and in reducing the associated mortality.

 

With the ageing of the population, the consequences of cardiac electrical dysfunction are major, both medically in terms of treatment needs and economically for society and public health spending.

 

Understanding these complex pathologies requires a multidisciplinary approach. In regrouping a large number of national and international experts at the same center, the Liryc fully responds to these 21st century demands.

Our creation

Liryc is one of six University Hospital Institutions created in France in 2011 as part of the ‘Investments for the Future’ program to boost medical research and innovation.

 

The institute benefited from financial support to make short-term investments and maintain its functioning on a long-term basis.

The Regional Council of Aquitaine also backed this project by providing financial support primarily for the construction of our technical and experimental platform.

Our gouvernance

Liryc is a partnership between the University of Bordeaux, Bordeaux University Hospital, Inria, INSERM and CNRS. It is managed by the Bordeaux University Foundation (FBU) umbrella foundation.

 

Liryc strategic and general guidelines are defined by a Supervisory Board and an International Scientific Board, relying on an executive committee for activity implementation and monitoring

Our partners

The French National Research Agency (ANR) provides funding for project-based research in France. They are responsible for project selection, funding and monitoring.

In 2011, ANR was the lead manager of the ‘Investments for the Future’ program for the creation of University Hospital Institutions (IHU), bringing together universities, health institutions and research centers. 

Six institutes were created with their principal aim being to boost French research in their particular field of expertise.

The General Commission for Investment (CGI) is in charge of implementing the Investments for the Future program to boost French competitiveness in higher education and research.

The creation of the University of Bordeaux marks the achievement of a common ambition for Bordeaux and the Aquitaine region: to offer a University open internationally with multidisciplinary training and innovative and structured research programs offered to all students, situated on a lively campus integrated within the city.

The University of Bordeaux is involved in the development of major projects to strengthen and maintain its position among the leading European universities. This ambition underpins the University’s  global strategy, also to be seen in its 2008  “Operation Campus” project. Accelerated in 2010 and 2011 by the response of key Bordeaux higher education and research centers to the “Investments of the future” program, it has been praised, honored and encouraged by the French Government. Consequently the University of Bordeaux was selected as one of the top 3 in the "Initiative of Excellence" program.

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The University Hospital of Bordeaux (CHU) comprises of three hospital sites in charge of health care for the Bordeaux and Aquitaine population.

The cardio-thoracic department combines specialist skills in cardiac and pulmonary pathologies affecting children and adults at two sites: Haut-Lévêque and Saint-André. It has a total capacity of 425 beds (including 22 places for out-patient admissions).

Medical and paramedical teams’ expertise is perfectly integrated to ensure all stages of patient care.

 

Inria is a public science and technology institution.

Inria consists of eight autonomous research centers across France. Three research centers collaborate with Liryc through the following teams that specialize   in signal processing and modeling.

  • The ASCLEPIOS team (Sophia Antipolis – Méditérannée)  , headed by Nicolas Ayache, is dedicated to bioimaging and modeling.
  • The CARMEN team (INRIA Bordeaux - Sud-Ouest),, headed by Yves Coudière, focuses on numerical models and methods for the simulation of cardiac electrophysiology, from the cellular to the individual level.
  • The GEOSTAT team (INRIA Bordeaux - Sud-Ouest),, headed by Hussein Yahia, is dedicated to signal processing.

CNRS is a national public research organization for basic research.

Liryc collaborates with two CNRS research units:

  • The UMR 5231 “​Laboratory for Molecular and Functional Imaging: From Physiology to Therapy”, headed by Chrit Moonen. This research unit undertakes basic research backed up by strong partnerships with clinical departments. Their aim is to develop new therapies by local hyperthermia, guided by MRI on intra-corporal targets, using focused ultrasounds from an external source.
  • The mixed CNRS-University Bordeaux UMR 5536 unit headed by Jean-Michel Franconi, whose principal aim is to develop novel applications of physical techniques in biology and medicine, with MRI as the main tool of research.

INSERM is a national structure exclusively focused on research on human health. 80% of research units are based in university hospitals.

The Bordeaux Cardio-Thoracic research center is a mixed research unit of Inserm and the  University of Bordeaux, U 1045, under the direction of Pr. Roger Marthan. It develops physiopathological and translational research focused on major fields of cardio-thoracic pathology, such as: asthma and chronic obstructive pulmonary disease (COPD), pulmonary hypertension (PH) and heart rhythm disorders.

The Bordeaux University Foundation (FBU) is an interface between the academic and socio-economic sectors. Through new forms of collaboration, the Foundation brings together businesses, associations, institutions and members of the public. These partnerships are funded by donations, in accordance with the Foundation’s objectives.

Its main aims are to support the professionalization, training and insertion of graduates, promote research excellence, increase the attractiveness of the Bordeaux campus and strengthen the internationalization of the University of Bordeaux.

Through its policy of encouraging and supporting innovation, the Regional Council of Aquitaine is today number one in France for the investment in research and innovation, and the 4th region for job and businesses creation.

As the third largest metropolitan region, it is also at the origin of the “Aquitaine Euskadi” Euroregion, the Iberian link of European construction.

Endowed with its numerous assets, Aquitaine is a territory of modernity, driven by a strong ambition for the future. This is embodied in voluntary regional policy where innovation in all its forms is central to every action.

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