Institution : Liryc - University of Bordeaux
Nationality : Canadian
Key-words : High Performance Computing; Cardiac Electrophysiology; Nonlinear Dynamics; Arrhythmia
Description of research interests or main activities
I perform detailed, multiscale simulations of cardiac electrical activity which requires knowledge of scientific computation and biophysics.
I have been developing simulation software, called CARP, for many years along with colleagues at Johns Hopkins and Graz. Detailed single cell ionic models form the basic unit of my models, which are then placed in geometrically accurate tissue structures to recreate organ level behaviour. Computational demands of such models are considerable and can require thousands of processors. Part of my research is on numerical techniques and algorithms to maximize performance of very large models.
I study both the atria and ventricles, with a focus on arrhythmia mechanisms and defibrillation. A particular interest of mine is the Purkinje system for which I have developed a unique representation. Working with clinicians and experimentalists, I aim to gain understanding, provide insight, and explore new therapies through in silico analysis.