Thermoablation of atrial fibrillation.
In the 1990s, Liryc's clinicians identified the sources of atrial fibrillation in the pulmonary veins. This discovery helped to develop a curative treatment for this disorder. It involves cauterising the pulmonary veins with a radiofrequency catheter to isolate these sources of arrhythmia. Other energies have recently become available: Cryotherapy, delivered with a balloon, and within the framework of experimental protocols, electroporation. This treatment has become the standard treatment: to date, more than 400,000 patients benefit from it each year worldwide. Liryc's clinicians hold the largest ablation volume (> 1000 / year) in France, considering that AF ablation represents 75% of the total volume.
Treatment of atrial fibrillation by alcoholization of the Marshall's veins
Studies have shown that the Marshall's ligament can be the centre of the heart's electrical dysfunction. It may therefore be a major target beyond the pulmonary veins in the treatment of atrial fibrillation. However, conventional ablation techniques do not ensure its complete destruction: it is in fact positioned on the external face of the atrial wall, and is moreover largely isolated from radiofrequency currents by a sheath of adipose tissue. To overcome this technical limitation, the suppression of the Marshall's ligament and the surrounding ganglia can be achieved by injecting alcohol into the Marshall's vein adjacent to it. At Liryc, this approach is systematically used in cases of persistent AF, in addition to isolating the pulmonary veins and linear lesions (roof and mitral isthmus). This innovative technique has proven to be both effective and safe.
Thermoablation of ventricular fibrillation.
Clinicians have also identified the triggers of sudden deaths from ventricular fibrillation. These sources are located in the heart's electrical system, called the Purkinje network. This electrical network of the heart is essential for cardiac contraction and only constitutes 2% of the heart's ventricular mass. The destruction of these sources of arrhythmia by thermoablation represents an innovative and curative approach to ventricular fibrillation to prevent sudden death.