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Marc Strik



Marc Oliver Strik

Hospital Clinician
Liryc - Bordeaux University Hospital – University of Bordeaux




Cardiologist at Bordeaux University specialized in Cardiac Implantable Electronical Devices, trained at Maastricht University Medical Centre, skilled in cardiovascular implantable electric device troubleshooting and biomedical programming. He required a PhD at the Physiology Department at Maastricht University on 'Electrical Substrate for Cardiac Resynchronization Therapy'. He developed extensive three-dimensional mapping systems in animal models under guidance of Prof. Dr. Prinzen and Prof. Dr. Auricchio. He obtained research grants from the Dutch Heart Foundation and Netherlands Heart Institute which allowed him to perform a post-doc fellowship at the Service de Cardiologie-Electrophysiologie et Stimulation Cardiaque at Bordeaux University under supervision of Prof. Dr. Bordachar and Prof. Dr. Haïssaguerre. At Bordeaux University, he investigated a novel non-invasive three-dimensional electrical mapping system in dyssynchronous heart failure patients, performed multiple telemonitoring studies on pacemaker/ICD algorithms, co-wrote multiple ECG and pacemaker/ICD books in three languages and aided in production of >50 instructional videos on pacemaker/ICD programming. Resuming his cardiology training at Maastricht University Medical Center he conducted clinical studies on the electrophysiological effects of haloperidol and on remote monitoring of implantable cardioverter defibrillators connecting the Maastricht and Bordeaux hospitals.  After completing his training in February 2020, he started working as an electrophysiologist at Haut Lévèque Cardiology Hospital, Bordeaux University with a permanent position. Here he continues to specialize in remote medicine, education and clinical research. He also discovered his passion for connected devices. He performed a clinical study investigating diagnostic accuracy the Apple Watch ECG in 300 patients. The first results are published in the world renowned medical journal, Circulation. He also co-wrote the world’s first book on Apple Watch ECGs named Learn how to read an ECG based on smartwatch recordings: clinical cases from the Apple Watch. While he greatly enjoys working in France, he finds it challenging as the salary is very low, the system is archaic and bureaucratic and the French language is ever demanding. Since he is born in Tunesia and has visited Dubai multiple times since his brother lives there, he is now ready and looking forward for a Middle Eastern adventure.



  • the Dutch Society of Physiology awarded him the Young Physiologist Award three times
  • he founded, an online learning portal which is now part of the curriculum and is currently used by hundreds of medical students at Maastricht University
  • he founded, an online learning portal about electrocardiogrammes in French
  • he founded, an online learning portal in English about pacemakers, implantable cardioverter defibrillators and cardiac resynchronization therapy
  • his cardiology cases are appreciated on social media where he has over 4000 followers
  • he won the silver medal at the EHRA 2019 “device interrogation open”
  • with 38 peer reviewed publications and over 30 presentations at international conferences, he developed a good base to becoming an established clinical investigator


  1. Mills RW, Cornelussen RN, Mulligan LJ, Strik M, Rademakers LM, Skadsberg ND, van Hunnik A, Kuiper M, Lampert A, Delhaas T, Prinzen FW. Left ventricular septal and left ventricular apical pacing chronically maintain cardiac contractile coordination, pump function and efficiency. . Circulation. Arrhythmia and electrophysiology. 2009
  2. Rademakers LM, van Kerckhoven R, van Deursen CJ, Strik M, van Hunnik A, Kuiper M, Lampert A, Klersy C, Leyva F, Auricchio A, Maessen JG, Prinzen FW. Myocardial infarction does not preclude electrical and hemodynamic benefits of cardiac resynchronization therapy in dyssynchronous canine hearts. Circulation. Arrhythmia and electrophysiology. 2010;3:361-36          
  3. Strik M, Ploux S, Vernooy K, Prinzen FW. Cardiac resynchronization therapy: Refocus on the electrical substrate. Circ J. 2011;75:1297-1304      
  4. Strik M, Rademakers LM, van Deursen CJ, van Hunnik A, Kuiper M, Klersy C, Auricchio A, Prinzen FW. Endocardial left ventricular pacing improves cardiac resynchronization therapy in chronic asynchronous infarction and heart failure models. Circulation. Arrhythmia and electrophysiology. 2012;5:191-200     
  5. Strik M, van Middendorp LB, Vernooy K. Animal models of dyssynchrony. J Cardiovasc Transl Res. 2012;5:135-145                                               
  6. Strik M, Regoli F, Auricchio A, Prinzen F. Electrical and mechanical ventricular activation during left bundle branch block and resynchronization. J Cardiovasc Transl Res. 2012;5:117-126   
  7. van Deursen CJ, Strik M, Rademakers LM, van Hunnik A, Kuiper M, Wecke L, Crijns HJ, Vernooy K, Prinzen FW. Vectorcardiography as a tool for easy optimization of cardiac resynchronization therapy in canine left bundle branch block hearts. Circulation. Arrhythmia and electrophysiology. 2012;5:544-552
  8. Strik M, van Deursen CJ, van Middendorp LB, van Hunnik A, Kuiper M, Auricchio A, Prinzen FW. Transseptal conduction as an important determinant for cardiac resynchronization therapy, as revealed by extensive electrical mapping in the dyssynchronous canine heart. Circ Arrhythm Electrophysiol. 2013    
  9. Lumens J, Ploux S, Strik M, Gorcsan J, 3rd, Cochet H, Derval N, Strom M, Ramanathan C, Ritter P, Haissaguerre M, Jais P, Arts T, Delhaas T, Prinzen FW, Bordachar P. Comparative electromechanical and hemodynamic effects of left ventricular and biventricular pacing in dyssynchronous heart failure: Electrical resynchronization versus left-right ventricular interaction. J Am Coll Cardiol. 2013;62:2395-2403
  10. Strik M, van Middendorp LB, Houthuizen P, Ploux S, van Hunnik A, Kuiper M, Auricchio A, Prinzen FW. Interplay of electrical wavefronts as determinant of the response to cardiac resynchronization therapy in dyssynchronous canine hearts. Circulation. Arrhythmia and electrophysiology. 2013;6:924-931              
  11. van Middendorp LB, Strik M, Houthuizen P, Kuiper M, Maessen JG, Auricchio A, Prinzen FW. Electrophysiological and hemodynamic effects of vernakalant and flecainide during cardiac resynchronization in dyssynchronous canine hearts. Journal of cardiovascular pharmacology. 2014;63:25-32   
  12. Ploux S, Strik M, van Hunnik A, van Middendorp L, Kuiper M, Prinzen FW. Acute electrical and hemodynamic effects of multisite left ventricular pacing for cardiac resynchronization therapy in the dyssynchronous canine heart. Heart Rhythm. 2014;11:119-125
  13. van Middendorp LB, Strik M, Houthuizen P, Kuiper M, Maessen JG, Auricchio A, Prinzen FW. Electrophysiological and haemodynamic effects of vernakalant and flecainide in dyssynchronous canine hearts. Europace. 2014 Jan 30  
  14. Vernooy K, van Deursen CJ, Strik M, Prinzen FW. Towards better application of Cardiac Resynchronization Therapy: new evidence, remaining disputes and novel directions. Nat Rev Cardiol. 2014  Aug;11(8):481-93
  15. Strik M, Defaye P, Eschalier R, Mondoly P, Frontera A, Ritter P, Haïssaguerre M, Ploux S, Ellenbogen KA, Bordachar P. Performance of a specific algorithm to minimize right ventricular pacing: A multicenter study. Heart Rhythm. 2016 Jun;13(6):1266-73
  16. Saporito S, van Assen HC, Houthuizen P, Aben JP, Strik M, van Middendorp LB, Prinzen FW, Mischi M. Assessment of left ventricular mechanical dyssynchrony in left bundle branch block canine model: Comparison between cine and tagged MRI. Magn Reson Imaging. 2016 Oct;44(4):956-63
  17. Strik M, Frontera A, Eschalier R, Defaye P, Mondoly P, Ritter P, Haïssaguerre M, Ploux S, Bordachar P Accuracy of the pacemaker-mediated tachycardia algorithm in Boston Scientific devices. J Electrocardiol. 2016 Jul-Aug;49(4):522-9
  18. Ploux S, Strik M, Varma N,Lazarus I, Swerdlow C, Bordachar P. ICDs remote monitoring systems: proprietary specificities and consequences for patient care. JACC Clinical Electrophysiology, in press
  19. Welte N. Strik M, Frontera A, Eschalier R, Defaye P, Mondoly P, Ritter P, Haïssaguerre M, Ploux S, Bordachar P Multicenter Investigation of an Implantable Cardioverter Defibrillator Algorithm to Detect Oversensing. Heart Rhythm 2017 Jul;14(7):1008-1015.
  20. Engels EB, Strik M, van Middendorp LB, Kuiper M, Vernooy K, Prinzen FW. Prediction of optimal cardiac resynchronization by vectors extracted from electrograms in dyssynchronous canine hearts. J Cardiovasc Electrophysiol. 2017 Aug;28(8):944-95
  21. Huntjens PR, Ploux S, Strik M, Walmsley J, Ritter P, Haissaguerre M, Prinzen FW, Delhaas T, Lumens J, Bordachar P. Electrical Substrates Driving Response to Cardiac Resynchronization Therapy: A Combined Clinical-Computational Evaluation. Circ Arrhythm Electrophysiol. 2018 Apr;
  22. le Polain de Waroux JB, Ploux S, Mondoly P, Eschalier R, Strik M, Houard L, Pierre B, Buliard S, Klotz N, Ritter P, Haissaguerre M, Mahfouz K, Bordachar P. Defibrillation testing is mandatory in patients with subcutaneous implantable cardioverter-defibrillator to confirm appropriate ventricular fibrillation detection. Heart Rhythm. 2018 May;15(5):642-650.
  23. Strik M, Vernooy K, Prinzen FW. Too old to shock?: Questioning added benefit of ICD in elderly CRT patients. Int J Cardiol. 2018 Jul 15;263:65-6
  24. Ploux S, Varma N, Strik M, Lazarus A, Bordachar P. Optimizing Implantable Cardioverter-Defibrillator Remote Monitoring: A Practical Guide. JACC Clin Electrophysiol. 2017 Apr;3(4):315-328
  25. Ploux S, Swerdlow CD, Strik M, Welte N, Klotz N, Ritter P, Haïssaguerre M, Bordachar P. Towards eradication of inappropriate therapies for ICD lead failure by combining comprehensive remote monitoring and lead noise alerts. J Cardiovasc Electrophysiol. 2018 Aug;29(8):1125-1134
  26. Strik M, Ploux S, Huntjens PR, Nguyên UC, Frontera A, Eschalier R, Dubois R, Ritter P, Klotz N, Vernooy K, Haïssaguerre M, Crijns HJGM, Prinzen FW, Bordachar P. Response to cardiac resynchronization therapy is determined by intrinsic electrical substrate rather than by its modification. Int J Cardiol. 2018 Nov 1;270:143-148
  27. Nguyên UC, Cluitmans MJM, Luermans JGLM, Strik M, de Vos CB, Kietselaer BLJH, Wildberger JE, Prinzen FW, Mihl C, Vernooy K.  Visualisation of coronary venous anatomy by computed tomography angiography prior to cardiac resynchronisation therapy implantation. Neth Heart J 20, 2018
  28. Strik M, Socié Pierre, Ploux S, Bordachar P, Unexpected and undesired side-effects of pacing algorithms during exercise, J Electrocardiol. 2018 Nov - Dec;51(6):1023-1028
  29. Welte N, Gang ES, Swerdlow CD, Strik M, Bordachar P, Ploux. Inappropriate disabling of an ICD noise-detection algorithm in pacemaker-dependent patients. S. Pacing Clin Electrophysiol. 2019 Apr;42(4):478-482.
  30. Nguyên UC, Cluitmans MJM, Strik M, Luermans JG, Gommers S, Wildberger JE, Bekkers SCAM, Volders PGA, Mihl C, Prinzen FW, Vernooy K. Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning. Europace. 2018 Dec 24.
  31. Strik M, den Uijl D, Vernooy K, Luermans J. Unsuccessful antitachycardia pacing: What is the mechanism? Pacing Clin Electrophysiol. 2019 Apr;42(4):464-466.
  32. Willemen E, Schreurs R, Huntjens PR, Strik M, Plank G, Vigmond E, Walmsley J, Vernooy K, Delhaas T, Prinzen FW, Lumens J. The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach. Front Physiol. 2019 Feb 1;10:17.
  33. Echocardiographic Assessment of Left Bundle Branch-Related Strain Dyssynchrony: A Comparison With Tagged MRI. Fixsen LS, de Lepper AGW, Strik M, van Middendorp LB, Prinzen FW, van de Vosse FN, Houthuizen P, Lopata RGP. Ultrasound Med Biol. 2019 Aug;45(8):2063-2074. doi: 10.1016/j.ultrasmedbio.2019.03.012. Epub 2019 May 3.
  34. Non-invasive cardiac mapping for non-response in cardiac resynchronization therapy. Strik M, Ploux S, Jankelson L, Bordachar P. Ann Med. 2019 Mar;51(2):109-117. doi: 10.1080/07853890.2019.1616109. Epub 2019 May 23
  35. Oversensing issues leading to device extraction: When subcutaneous implantable cardioverter-defibrillator reached a dead-end. Noel A, Ploux S, Bulliard S, Strik M, Haeberlin A, Welte N, Marchand H, Klotz N, Ritter P, Haïssaguerre M, Bordachar P. Heart Rhythm. 2020 Jan;17(1):66-74. doi: 10.1016/j.hrthm.2019.07.004. Epub 2019 Jul 8.
  36. Electrogram morphology discriminators in implantable cardioverter defibrillators: A comparative evaluation. Frontera A, Strik M, Eschalier R, Biffi M, Pereira B, Welte N, Chauvel R, Mondoly P, Laborderie J, Bernis JP, Clementy N, Reuter S, Garrigue S, Deplagne A, Vernooy K, Pillois X, Haïssaguerre M, Dubois R, Ritter P, Bordachar P, Ploux S. J Cardiovasc Electrophysiol. 2020 Jun;31(6):1493-1506. doi: 10.1111/jce.14518. Epub 2020 May 7
  37. Validating QT-Interval Measurement Using the Apple Watch ECG to Enable Remote Monitoring During the COVID-19 Pandemic. Strik M, Caillol T, Ramirez FD, Abu-Alrub S, Marchand H, Welte N, Ritter P, Haïssaguerre M, Ploux S, Bordachar P. Circulation. 2020 Jul 28;142(4):416-418. doi: 10.1161/CIRCULATIONAHA.120.048253. Epub 2020 Jun 1.
  38. Should we still monitor QTc duration in frail older patients on low-dose haloperidol? A prospective observational cohort study. Castro E, Körver F, Merry A, van Moorsel F, Hazebroek M, Smid M, Ploux S, Bordachar P, Prinzen F, Sipers W, Strik M. Age Ageing. 2020 Jul 2:afaa066. doi: 10.1093/ageing/afaa066. Online ahead of print.



Prinzen FW, Strik M, Regoli F, Auricchio A.
Basic physiology and hemodynamics of cardiac pacing (chapter 9). 
In: Ellenbogen KA, ed. Clinical cardiac pacing, defibrillation, & resynchronization therapy. 2011.


L'ECG à l'ECN en 75 tracés.
P. Bordachar, R. Chuavel, M.Strik, A. Ximenes.


E.C.G. I; ECG normal et pathologique ECG des douleurs thoraciques ECG des cardiomyopathies.
P. Bordachar, D. Ploux, M. Strik.


E.C.G. II; Troubles de la conduction Troubles du rythme 
P. Bordachar, S. Ploux, M. Strik.


E.C.G I (EN) Section 1 : normal and pathological ECG Section 2 : Chest pain Section 3 : Cardiomyopathies.
P. Bordachar, S. Ploux, M. Strik.


E.C.G. II (EN) : Conduction and rhythm disorders.
P. Bordachar, S. Ploux, M. Strik.


Encyclopédie Boston Scientific: Encyclopédie dédiée aux spécificités de l'interrogation et de la programmation des dispositifs Boston Scientific.
Pr Pierre Bordachar, Pr Romain Eschalier, Dr Sylvain Ploux, Dr Marc Strik.


ECG interpretatie: Ritme - en geleidingsstoornissen
Dr Marc Strik et Prof Pierre Bordachar.


Learn how to read an ECG based on smartwatch recordings: clinical cases from the Apple Watch
Prof Pierre Bordachar, Dr Marc Strik, et al.


Apprendre à lire un ECG avec une montre connectée: cas cliniques basés sur des tracés Apple Watch (édition noir et blanc)
Pr Pierre Bordachar, Dr Marc Strik, et al.