A major breakthrough in the treatment of cardiac arrhythmias has just been published: CT-guided catheter ablation is revolutionizing patient care. The “InEurHeart” clinical trial, coordinated by Prof. Sacher and Prof. Hubert Cochet, reveals that this method, which uses a “digital twin” of the heart, significantly reduces the duration and complexity of procedures.

Technological innovation serving cardiology

On February 11, 2026, the prestigious European Heart Journal published the results of the InEurHeart study. This multicenter randomized clinical trial, conducted in 14 European centers (France, Germany, Switzerland, and Austria), focused on the treatment of ventricular tachycardia in patients with a history of myocardial infarction.

The innovation is based on cutting-edge technology developed by the start-up InHeart (a spin-off of the Liryc institute). Thanks to artificial intelligence, doctors can now create a detailed 3D model, also known as a “digital twin,” of the patient’s heart prior to surgery. This model precisely locates the scarred areas responsible for arrhythmias, enabling optimal preparation for CT-guided catheter ablation.

Convincing clinical results for patients with ventricular tachycardia

The study compared CT-guided catheter ablation with the conventional method in a sample of 113 patients.

The findings mark a turning point for clinical practice:

• Reduction in intervention time: the average duration of the operation fell from 149 minutes to 120 minutes, a decrease of 19% (and up to 28% in per-protocol analysis).

• Increased effectiveness: the success rate corresponding to no recurrence at one year is 77% with CT-guided catheter ablation, compared to 67% for the conventional method.

• Reduction in arrhythmia burden: the number of arrhythmia episodes fell by 90% in the group receiving 3D imaging.

• Safety confirmed: major complications remained rare and similar in both groups (1.8% vs. 3.5%), validating the safety of this new attachment.

A major public health issue

Ventricular tachycardia is a major medical challenge. While millions of people now have implantable defibrillators to correct arrhythmias, only a minority undergo ablation, which is a more lasting solution.

Traditionally, this procedure is complex and relies heavily on the practitioner’s expertise to identify the areas to be treated in real time. By integrating scanner guidance and AI, the InEurHeart project—a collaboration between Bordeaux University Hospital, IHU Liryc, the University of Bordeaux, and INRIA—simplifies the procedure and could broaden access to this essential treatment.